Immunologic challenges of human reproduction: an evolving story

Chronic urticaria: an evolving story.

Albuminuria and diabetic nephropathy: an evolving story.

PIDs and cancer: an evolving story.

PIDs and cancer: an evolving story ---------------------------------------------------------------------------------------------------------------Luigi D. Notarangelo HARVARD MEDICAL SCHOOL Analysis of overall and site-specific cancer risk in patients with primary immunodeficiency diseases (PIDs) may shed light on the role played by the immune system in controlling malignancies. The association...

HIF2 and endocrine neoplasia: an evolving story.

In this issue of Endocrine-Related Cancer, Toledo et al. report the identification of activating mutations in the HIF2 (EPAS1) transcription factor in a subset of sporadic pheochromocytomas and paragangliomas. These findings add significantly to an evolving and complex story of the role of hypoxic gene response pathways in human endocrine neoplasia.

Antiphospholipid Syndrome – An Evolving Story of a Multisystemic Disease